It has been found by a team of researchers at Washington University in St. Louis that genes linked to early-onset Alzheimer's disease can also be seen in people with late-onset Alzheimer's disease. It is being said that rare variants of three different genes are very common in patients suffering from Alzheimer's disease.

The report has found that Alzheimer’s tends to spread in the body through the brain. The team of researchers had conducted the study to find out how an abnormal protein in the disease could cause destruction in the brain. In order to examine the same, researchers created mice that were genetically engineered.

As per the report findings, Alzheimer’s is related to two kinds of abnormal proteins, of which one is tau and the other one is beta amyloid. The researchers created mice with abnormal tau protein in the entorhinal cortex of their brain. It was done on the evidence that patients with Alzheimer’s disease show the substance at first in this region of brain only.

It was found by the lead researcher, Karen Duff that high levels of beta amyloid that could be easily detected through imaging tools, can help in diagnosis of the disease. Whereas the other abnormal protein i. e. tau is closely related to dementia. She told that if path of Tau would be known to them, the treatment of Alzheimer’s disease could be enhanced in the future.

However, the team could not find the way how both the abnormal proteins interacted with each other. It was assumed by Ms. Duff after the research that their interaction in some or the other way led to killing of the cells in the brain. “There’s some interaction, and it seems amyloid has its detrimental effects through tau”, she said.